Endocrine Abstracts

Hypercorticism is a syndrome caused by extended and very high exposure of glucocorticoids to the body. ACTH-dependent Cushing’s syndrome develops as a result of the overproduction of adrenocorticotropic hormone by the pituitary adenoma. The main treatment for ACTH-dependent Cushing’s is transnasal transsphenoidal removal of the pituitary adenoma. A the same time, the recurrence rate of Cushing syndrome is observed up to 3% during the year and up to 3% –22% of...

Target.: To study the incidence of postoperative complications in patients with transsphenoidal pituitary adenoectomy.Materials and research methods: 180 cases of PA subjected to TРА for the period from 2018 to 2020 were analyzed. Of these, 102 (56.6) women, 78 (43.3) men, patients were divided into two alternative groups: the first group - 93 (51.6%) patients with macroadenomas - 42 (45.2%) men, women 51 (54.8%), the second (comparison group) - ...

Cushing’s is a challenging disease to diagnose. The diagnosis is often delayed because Cushing’s is frequently masked by its overlap with more common medical problems such as diabetes, high blood pressure, obesity and polycystic ovary syndrome. Cushing’s may be more common than previously thought. The patient is a 15-year-old girl who developed symptoms of hyperandrogenia about 3 years prior to her visit to the Endocrine medical research Center, Uzbekistan. The ...